How to calculate days supply, worked for the dosage forms that actually catch people out — eye drops, insulin and inhalers — plus the rounding rule and the dimensional-analysis setup that stops the error before the arithmetic.
Days supply = total quantity dispensed divided by the amount used per day. To calculate total quantity needed:
Worked example — oral solid, splitting
Amoxicillin 500 mg PO TID × 7 days. Stock: 250 mg capsules.
500 mg = 2 × 250 mg capsules per dose.2 × 3 = 6 capsules/day.6 × 7 = 42 capsules.Worked example — 24-hour hospital supply
Enalapril 5 mg PO BID. Stock: 5 mg tablets. 1 × 2 = 2 tablets / 24 h.
Clindamycin 300 mg PO q6h. Stock: 150 mg capsules. 2 capsules × 4 doses/day = 8 capsules / 24 h.
A standard workflow the PTCE® likes. Assume 1 mL = 20 drops unless told otherwise.
Tobramycin ophthalmic, 2 drops in each eye six times daily × 7 days. Bottle = 5 mL.
4 drops (both eyes).4 × 6 = 24 drops.24 × 7 = 168 drops.168 ÷ 20 = 8.4 mL.8.4 ÷ 5 = 1.68, round up to 2 bottles.Always round up on ophthalmic dispensing — bottle loss during administration is expected.
| Value | Tenths | Hundredths | Thousandths |
|---|---|---|---|
| 7.84621 | 7.8 | 7.85 | 7.846 |
| 0.67891 | 0.7 | 0.68 | 0.679 |
| 15.20494 | 15.2 | 15.20 | 15.205 |
| 42.33338 | 42.3 | 42.33 | 42.333 |
Rule: look one place to the right of where you want to round — if that digit is 5 or greater, round up; if it is 4 or less, round down.
Practical rounding: the number must be measurable. Do not round to 3.847 mL if the dispensing device is a 5 mL oral syringe with 0.5 mL markings. Do not round to 7.3 days when the prescription is written in whole days.
A calculation method that handles conversions, dose calculations, and IV rates in one chain of fractions.
Five steps
Worked example — pediatric dose
Diphenhydramine 5 mg/kg/day. Child weighs 35 lb. How many mg/day?
mg = (5 mg / kg / day) × (1 kg / 2.2 lb) × 35 lb × 1 day.(5 × 35) / 2.2 = 79.5 mg/day.Worked example — drops/min
0.5 L infused over 2 hours; infusion set 10 gtt/mL.
drops/min = (10 gtt / mL) × (0.5 L / 2 hr) × (1,000 mL / 1 L) × (1 hr / 60 min).= (10 × 0.5 × 1,000) / (2 × 60) ≈ 42 gtt/min.All Order Entry and Processing guides · What is on the PTCE and how it is weighted · The Federal Requirements domain